Victor Frankenstein and his dog Sparky are discovered and rescued by surgeon Victor Van Dort from a degrading life as circus freaks and are given a chance to live their last years with comfort, respect and dignity. Based on David Lynch's The Elephant Man and the true story of Joseph Merrick.

Victor Van Dort's son, Victor (Frankenweenie) is mourning over the loss of his dog. But what happens when Emily appears to him in a dream, and tells him how he could bring his dog back to life? And what happens when not only animals are raised from the dead in this adventure?