Lestrade tells Sherlock about a case of what appears be vampires in the UK. At first, Holmes is dubious about the case, but as he examines the victims, more and more details come to light that lure Holmes closer to the killer behind this brutal string of murders; but not everything is as it seems, and if John and Sherlock are going to survive, they must team up with an unusual ally

Sherlock met a man who claimed to be a vampire once. The man warned him of others like himself, the vampaneze. Sherlock always thought it was a load of rubbish until one of them turns up at Baker Street almost thirty years later.