Dante takes a job as a security guard at Cross Academy, where humans and vampires attend highschool. He thought it ould be an easy job, but he didn't know about vampire fangirl Yuki Cross and how hard she would make his life.

Tsuki is a new student at Devil High and while there she meets Chihiro a young girl who has the weridest of past lives. Tsuki thought she wouldn't make to many friends, but found a lot thanks to her carring for Chihiro, she also gets a boyfriend.

Zero has an incurable illness. Dante and Nero love to tease him about it. Dante/Nero/Zero

Luna was a little girl and her family was attacked. She loses her sister and finds a new family of Vampires! She becomes a hunter to avenge her family and finds some friends and more problems.