After Mr Swackhammer hired the Nerdlucks and Tom's school enemies to take over the world, Looney Tunes team up with the Tom and Jerry Squad. How will both comedy teams work well with each other? Will Jerry cooperate with Tweety? Can both used to be friends Tom and Bugs Bunny team up again to finish their enemies? Rated T for violence and bit of blood.

Sylvester meets Tom when he accidentally winds up at his house. They help each other to catch their meals but when a female cat enters the stage along with Bugs Bunny and Pepe Le Pew, jealousy ensues.