Soul Society was disorienting, most of the buildings looking exactly the same. That's why it was difficult for Orihime to know which direction to go when her companion urgently advised her to run this direction or that to escape a crowd of low-ranking Shinigami.

After a while, it didn't matter to Orihime that they were fugitives on the run and that their lives were in danger. Ishida was naturally suited to quick thinking, while Orihime hesitated - because of this, he'd taken to grabbing her hand to get her into a safer area.

With their hands together, little else mattered.