Disclaimer – I own nothing of Grey's Anatomy, except my original characters and plot. The rest belongs to the creators of Grey's Anatomy.

Italics are lyrics and flashbacks

A/N: I was watching a few episodes of Grey's Anatomy and decided to try my hand at a Grey's Anatomy fic.

Summary: AU: Meredith and Derek have finally settled down and are expecting their first child together and discover the true meaning of family. My first attempt at a Grey's Anatomy fic, so bare with me, please. Either three or four shot.

Rating: T

Genre: General/None

(chapter title – The Beginning)

Meredith Shepherd smiled at her husband, the very successful Dr. Derek Shepherd. The two of them were in bed, naked from the waist down.

"Mer, sweetie – are you sure about this?" Derek asked his wife, running his hands up and down her ribcage. Meredith nodded and watched as Derek took off his sweatpants and put a condom on before going inside Meredith.

After eight hours of lovemaking, Meredith felt herself grow tired, but she wouldn't let herself fall asleep. Derek gave a final thrust and pulled out.

"Shit." He swore under his breath.

"What?" Meredith inquired, drawing the blankets around her.

"The condom broke." Derek answered, throwing the torn condom away before getting out of bed and walked to the bathroom across the hall to wash his hands. Meredith propped herself up on her elbow and waited for her husband to join her. He joined her thirty seconds later, kissing her forehead as he climbed in next to her.

"I love you." Meredith whispered, running her hands through Derek's hair.

"I love you, too." Derek told her, kissing her hands.

Two weeks later, something wasn't right – Meredith spent the entire day in the bathroom, throwing up. Derek felt torn – he was needed at work, but Meredith needed him more.

"Mer, you okay?" Derek inquired, knocking softly on the bathroom door.

"I will be – I think it was something I ate yesterday." Meredith answered, her voice muffled.

"I'm going into work for a while – call if you need anything." Derek told her.

"I will." Meredith answered.

At work, Derek went directly to the Pedriatric Ward. Arizona Robbins and Alex Karev were there as well, looking over their charts for that morning. Derek looked at his chart and went to his first room, whistling a happy tune.

Upon entering the patient's room, he stopped whistling and looked at the sickly little girl on the bed in front of him. According to his charts, her name was Sophie and she had stage three leukemia.

"How is she, doctor?" Sophie's mother asked, entering the room, a coffee cup in her hand.

"She's hanging on, Mrs. Nobel." Derek answered, taking Sophie's vitals.

"Will she die?" a young-sounding voice inquired. Derek looked down and saw Sophie's younger sister, Sarah, clinging to her mother's leg. Derek knelt down and smiled at the young girl.

"What's your name?" Derek asked.

"Sarah." The girl replied.

"Well, Sarah, I can't give you a straight answer right now."

"I don't want her to die." Sarah said, tears in her beautiful blue eyes.

"May I hold her?" Derek asked Mrs. Nobel. She nodded and Derek carefully picked up the young girl, holding her close.

"Your sister is going to be just fine." Derek half-lied. He knew that Sophie had little chance to live without a bone marrow transplant – no one in Sophie's family was a match, so that was very difficult.

"I believe you doctor." Sarah told Derek, kissing his cheek. Derek smiled and put Sarah back down.

"I'm going to check on the rest of my patients then I'll be back." Derek told the Nobel family. Mrs. Nobel nodded and sat in the chair next to Sophie's bed.

It was after lunch and Derek was about to go on afternoon rounds when his cell phone rang. Looking at the caller ID, it was Meredith. He went into the on-call room and closed the door behind him.

"Hello?" Derek whispered.

"Derek? It's me." Meredith's sweet voice was on the other line.

"Meredith, are you okay?" Derek questioned, feeling some panic in his voice.

"I'm fine – I just threw up for the tenth time today and I have a headache."

"Do you want me to come home?" Derek inquired.

"No, but I was wondering what time you were coming home."

"I don't know, Mer." Derek answered.

"Okay – I love you."

"Love you, too."

Derek hung up his phone and put it back in his breast pocket. He then exited the room and went back to work.

A week later, it was confirmed that Meredith was pregnant. Derek gently kissed Meredith's stomach and looked into her deep green eyes.

"I hope we have a daughter." Derek said, holding Meredith that night.

"Why?" Meredith asked, rubbing her thumb up and down Derek's hand.

"I was the only boy in a family of five and I love my sisters dearly."

"I want a son." Meredith said, running a hand through Derek's hair.

"I suppose either one would be great." Derek told her, kissing her forehead.

It turned out at Meredith's doctor's appointment that they were expecting twins – one boy and one girl. Meredith kissed Derek on the lips and looked down at her stomach.

"Looks like we each got what we wanted." Derek whispered in Meredith's ear. Meredith nodded and watched Derek's hand make its way over her stomach.

"What are you doing?" Meredith inquired, lifting her head slightly off her pillow.

"Just wondering what our children are doing in there." Derek answered, smiling at his wife.

Nine months later, Meredith went into labor at 8:00 in the morning. Derek rushed Meredith to the hospital and got her checked into a hospital room.

He spent all of Meredith's twenty-six hour labor with her, refusing to leave her side. Their son was born first, followed by their daughter.

"They're beautiful." Derek whispered, motioning that he wanted to hold a baby. Meredith smiled and handed him the baby wrapped in a pink blanket.

After an hour of arguing about baby names, they finally settled on April Rose Shepherd and Sean Eric Shepherd for the twins.

"I love the names we picked for them – they're perfect." Derek told Meredith, putting April in her basinet, put Sean in his and climbed in next to Meredith.

An hour later, there was a knock on the door. Derek quickly went to answer it. On the other side were Callie, Arizona, Cristina, Owen, Izzie, Alex, Lexie and Mark. Behind them, were Dr. Bailey and Dr. Webber.

"Hey everyone." Derek whispered, watching everyone file into the room.

"So?" Izzie inquired, raising an eyebrow.

"What?" Derek asked.

"Where are the babies?" Cristina demanded, looking around the room.

"They're sleeping, so is Meredith." Derek's voice remained in a whisper so that he wouldn't wake up his sleeping family.

"Aww – they're adorable." Lexie whispered, making her way over to the basinets where the twins were sleeping.

"Thank you. Their names are April and Sean." Derek told his friends, gently picking up the babies and handed his daughter to Callie and his son to Lexie.

"Hi there little one." Callie cooed to April when she woke up. Derek rushed over and smiled when he saw his daughter awake.

After everyone left and the babies were down for the night, Derek climbed in next to Meredith and held her all through the night, promising that he would tend to the babies if they woke up.

The two of them looked at each other and smiled - they now had the perfect family.