The Lifestream, Mako, is the very lifeblood of the planet. It is the source of all new life that comes into being on Gaia. It nurtures new creatures into being and all that dies is returned to it. It contains all the memories, knowledge and emotions of every living being that has ever passed away.
In one particular time and place the Lifestream was depleted almost to the point of killing the planet, but the multiverse is a vast and varied thing. In another time and place, long before scientists ever considered using Mako as a power source, there was a... hiccup.
A change as small and insignificant as the displacement of air from the flapping of a butterfly's wings.
Nine months later, Dr Grimoire Valentine's wife gave birth to his first and only child, a child who he had decided would be named Vincent. However, due to that tiny, insignificant fluctuation in the Lifestream, the child was female.
I honestly don't know if I'll be continuing this very far; it's essentially a plotbunny at the moment. If you like it, review and it may go further.